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. 2020 Dec 16;61(14):22. doi: 10.1167/iovs.61.14.22

Figure 7.

Figure 7.

Treg injection improved prognosis of corneal alkali burns with reduced corneal fibrosis and decreased corneal neovascularization during the tissue remodeling stage. (A) The relative mRNA expression of Acta2, Col3a1, and tenascin C in corneas is shown. (B) ELISA examined the protein levels of TGF-β. (C) Representative immunofluorescence micrographs of corneal stroma stained with anti-α-SMA and collagen III on days 8 and 16 are presented. Scar bar: 100 µm. (D) Representative bright-field corneal images showed the development of neovascularization in the corneal limbal area at various time points. (E) Clinical scores of corneal neovascularization are summarized in the right panel. (F) Both mRNA and protein levels of VEGF A are shown. (G) Representative immunofluorescence micrographs of cornea stained with VEGF A on day 16 are presented. Scar bar: 100 µm.