Table 1.

Daily clinical and laboratory variables during ICU stay

Variables	Reference range	Day 1 admission			Day 3			Day 7		Day 10					Day14		Day21			Day 28			Day 40
SOFA		13			16			16		16					17		16			15			13
White blood counts (per μl)	(4800–10,800)	5,700			11,710			9990		8760					17,070		27,930			23,750			10,710
Lymphocytes(per μl)	(900–5200)	1000			700			800		400					800		1,200			800			1800
Neutrophils (per μl)	(1900–8000)	4,300			10,300			8,500		7700					12,600		23,600			21,100			6300
N/L		4.3			14.7			10.6		19.2					15.7		19.6			26.3			3.5
CRP (mg/dl)	(0–1)	17.7			31.9			18.6		14.3					25		17.1			8.65			8.80
Procalcitonin(ng/ml)	(0–0.5)	1.9			13			7.92		6.91					13.1		10			6.06			5.75
Glycemia (mg/dl)	(60–99)	124			96			96		70					92		96			86			96
D-dimer (mg/l)	(0–0.5)	1.9			4.3			0.8		1					2.6		2.7			6.1			7.64
Ferritin (ng/ml)	(26–388)	3216			3755			2012		1395					2128		2737			2084			–
NT-proBNP (pg/ml)	(0–125)	653			2147			2869		2801					3028		12,541			26,116			19,692
PaO2/FiO2		190			197			208		174					130		161			189			260
SARS-CoV-2 RT-PCR					Positive			Positive		Positive					Positive		Negative Negative after 24 h			Negative
BAS/BAL															Rhizopus spp.		Rhizopus spp.			Rhizopus spp.			Rhizopus spp.
Pleural effusion	Histo-pathology																						Negative
	Microbio-logy																						Negative

SOFA sequential organ failure assessment, N/L neutrophils/lymphocyte ratio, CRP C-reactive protein