Table 3.
Effect of A. polystachyus on the Body Weights, PCV, and Temperature of P. berghei Infected Mice in the 4-Day Suppressive Test
| Group | Temperature | Wight | Packed Cell Volume | ||||||
|---|---|---|---|---|---|---|---|---|---|
| D0 | D4 | % Change | D0 | D4 | % Change | D0 | D4 | % Change | |
| NC | 36.02±0.97 | 34.66±0.56 | 3.75±0.77 | 31.02±1.45 | 28.78±1,21 | 7.14±0.73 | 56.20±1.44 | 52.40±1.03 | 6.74±2.01 |
| 25mg/kg CQ | 36.20±1.03 | 36.06±1.00 | 0.37±1.03a*** | 30.32±0.97 | 29.98±0.34 | 1.18±1.00a* | 51.00±0.95 | 51.60±0.56 | −1.28±1.31a**** |
| 100g/kg | 37.08±0.59 | 36.16±0.85 | 2.47±0.99b* | 30.54±1.02 | 29.28±0.98 | 4.20±0.59 | 52.80±1.32 | 51.20±1.60 | 2.94±0.98 |
| 200mg/kg | 36.50±0.61 | 36.04±0.32 | 1.27±0.57a* | 24.74±0.54 | 23.68±0.58 | 4.53±0.32 | 56.80±0.88 | 55.60±0.89 | 2.10±0.49a* |
| 400mg/kg | 35.72±0.39 | 35.76±0.44 | −0.13±0.81a*** | 26.28±0.77 | 25.66±0.36 | 2.45±0.51a* | 56.00±0.64 | 54.80±1.22 | 2.10±0.76a* |
Notes: Values are presented as Mean ± SD (Standard Deviation). Statistical significance as compared to treatment control denoted by *p<0.05, **p<0.01, ***p<0.001, and ****p<0.0001; aCompared to NC bCompared to CQ.
Abbreviations: CQ, chloroquine diphosphate; NC, normal control; D0, a day infection initiated; D4, 5th day of infection.