Table 7.
Effect of A. polystachyus Crude Extract on the Body Weights, PCV, and Temperature of P. berghei Infected Mice in the Prophylactic Test
| Group | Temperature | Wight | Packed Cell Volume | ||||||
|---|---|---|---|---|---|---|---|---|---|
| D0 | D4 | % Change | D0 | D4 | % Change | D0 | D4 | % Change | |
| NS | 36.60±0.48 | 34.06±0.52 | −6.88±1.77 | 29.80±1.18 | 26.88±0.93 | −9.55±1.89 | 57.60±0.87 | 48.00±1.23 | 16.63±0.76 |
| 25mg/kg CQ | 36.08±0.41 | 36.48±0.33 | 1.14±1.13a**** | 28.80±0.83 | 28.99±0.86 | 0.66±0.67a**** | 55.60±1.86 | 55.40±0.98 | 0.24±0.31a**** |
| 100mg/kg | 36.14±0.22 | 35.24±0.27 | −2.49±0.46 | 29.36±0.42 | 28.10±0.45 | −4.28±0.82a*, b* | 57.20±1.28 | 54.60±0.59 | 4.53±0.97a** |
| 200mg/kg | 36.48±0.44 | 35.58±0.48 | −2.46±0.77 | 31.48±0.96 | 30.66±0.80 | −2.54±0.52a*** | 54.80±1.77 | 53.80±1.32 | 1.76±1.32a**** |
| 400mg/kg | 36.02±0.38 | 35.68±0.59 | −0.96±0.92a** | 30.78±1.75 | 30.40±1.34 | −1.31±0.82a**** | 55.60±1.07 | 55.20±0.98 | 0.74±1.04a**** |
Notes: Values are presented as Mean ± SD (Standard Deviation). Statistical significance as compared to treatment control denoted by *p<0.05, **p<0.01, ***p<0.001, and ****p<0.0001; aCompared to NC; bCompared to CQ.
Abbreviations: CQ, chloroquine diphosphate; NC, normal control; D0, a day infection initiated; D4, 5th day of infection.