Abbreviations: Y – Yes; N – No; P – Partial Yes; NA – Not Applicable
*The AMSTAR 2 Checklist consists of 16 items and is rated based on the presence of weaknesses in critical domains. There is no overall score. [8]
Description of the numbered items:
1. Research question and inclusion criteria include components of PICO
2. Systematic review methods were established a priori
3. Selection of study design explained
4. Comprehensive literature strategy used
5. Study selection performed in duplicate
6. Data extraction performed in duplicate
7. List of excluded studies with explanation provided
8. Included studies described in adequate detail
9. Risk of Bias (RoB) in individual studies assessed
10. Funding source of included studies provided
11. Meta-analysis conducted using appropriate methods
12. Potential impact of RoB on the Meta-analysis assessed
13. Impact of RoB in individual studies on the review was discussed
14. Heterogeneity among studies was assessed and discussed
15. Publication bias assessed
16. Conflict of interest reported.