Table 1.
Demographic and clinical characteristics of osteoarthritis patients and controls. To identify demographic difference between groups ANOVA and t-tests were performed for continuous data, controls and OA groups, and between OA groups, 773 respectively. Chi-square tests were performed for categorical data. 6MWT= 6 Minute Walking Test; BMI = Body mass index; DN4 = Douleur Neuropathique en 4 questions; HADS = Hospital anxiety and Depression Scale; HOOS = Hip injury and Osteoarthritis Outcome Score; KOOS = Knee injury and Osteoarthritis Outcome Score, (ADL = Activities of Daily Living; SR = Sports and Recreation; QoL=Quality of Life); PCS= Pain Catastrophizing Scale; KL = Kellgren-Lawrence scale; TUG= stand up and go test.
| Controls | Knee OA | Hip OA | p value | ||||
|---|---|---|---|---|---|---|---|
| Subjects, n, % | 36 | 23 | 91 | 60 | 24 | 16 | |
| Age (years), mean, SD | 59.2 | 8 | 65.5 | 6.5 | 59.7 | 8.2 | <0.001** |
| Female, n, % | 20 | 55.5 | 72 | 79.1 | 8 | 33.3 | <0.001** |
| BMI (kg/m2), mean, SD | 27.8 | 4.6 | 30.4 | 4.9 | 28.3 | 3.7 | 0.06 |
| Education, n, % | 0.12 | ||||||
| Primary Education | 21 | 58.3 | 71 | 78 | 16 | 66.7 | |
| Secondary Education | 8 | 22.2 | 15 | 16.5 | 5 | 20.8 | |
| Post- secondary Education | 7 | 19.5 | 5 | 4.5 | 3 | 12.5 | |
| Smoking, n, % | 8 | 22.2 | 8 | 8.8 | 2 | 8.3 | 0.09 |
| Habitation, n, % | |||||||
| Alone | 6 | 16.7 | 17 | 18.7 | 3 | 12.5 | |
| Co-habitation | 30 | 83.3 | 74 | 81.3 | 21 | 87.5 | |
| Marital Status, n, % | 6 | 0.9 | |||||
| Married | 27 | 66.7 | 65 | 71.4 | 17 | 70.8 | |
| Never married | 3 | 8.3 | 5 | 5.5 | 2 | 8.3 | |
| Divorced | 2 | 5.6 | 7 | 7.7 | 2 | 8.3 | |
| Widowed | 4 | 11.1 | 14 | 15.4 | 3 | 12.5 | |
| Pain Duration (years), mean, SD | - | - | 7.7 | 6 | 5.1 | 4.3 | 0.015* |
| Pain Intensity (NRS), mean, SD | - | - | 6.6 | 1.7 | 6 | 1.6 | 0.1 |
| KOOS/HOOS, mean, SD | |||||||
| Symptom | - | - | 61.2 | 20 | 50.8 | 15 | 0.011* |
| Pain ADL | - | - | 63.7 | 15.6 | 55.9 | 17.8 | 0.061 |
| SR | - | - | 62.6 | 16.4 | 58.8 | 18.1 | 0.354 |
| QoL | - | - | 91.9 | 13.9 | 83.6 | 18.6 | 0.049* |
| - | - | 79.5 | 15.3 | 71.1 | 20.3 | 0.061 | |
| HADS, mean, SD | 0.354 | ||||||
| Anxiety | - | - | 8.8 | 5 | 6.8 | 4.4 | 0.061 |
| Depression | - | - | 7.1 | 4.1 | 6 | 4.6 | 0.354 |
| PCS, mean, SD | |||||||
| Rumination | 8.3 | 4.8 | 7.5 | 4. | 0.41 | ||
| Magnification | - | - | 5 | 3.7 | 4.4 | 3.4 | 0.43 |
| Helplessness | - | - | 10 | 7.5 | 8.4 | 6.2 | 0.34 |
| DN4, mean, SD | - | - | 2.8 | 2.2 | 1.8 | 1.5 | 0.029* |
| Physical Performance tasks, mean, SD | |||||||
| TUG, seg | - | ||||||
| 6MWT, meters | - | 13.6 | 4.2 | 270.8 | 68.4 | 0.4 | |
| - | - | 14.4 | 4.7 | 270.6 | 98.5 | 0.9 | |
| Radiographic KL, n, % | <0.001** | ||||||
| Grade 1 | - | - | 2 | 1.8 | 0 | 0 | |
| Grade 2 | - | - | 21 | 23.1 | 0 | 0 | |
| Grade 3 | - | - | 43 | 39.1 | 6 | 25 | |
| Grade 4 | - | - | 25 | 22.8 | 18 | 75 | |
*
p<0.05
**
p<0.001.