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. Author manuscript; available in PMC: 2020 Dec 17.
Published in final edited form as: J Cell Biochem. 2018 Sep 7;120(1):519–532. doi: 10.1002/jcb.27407

Fig. 3. Regulation of HNF4A-AS1 promoter by HNF4α.

Fig. 3.

(A) Luciferase reporter activities of HNF4A-AS1-Pro-P1-Luc induced by 0, 3 and 10 ng P1 & P2 HNF4α in HEK293 cells. N=4, mean ± SE. * p<0.05 vs control group. † p<0.05 vs 3 ng P1-HNF4α; (B & C) Comparison of reporter activities of HNF4A-AS1-Pro-Luc, HNF4A-P1–5’UTR-Luc, and HNF4A-Dis-P1–5’UTR-Luc with/without HNF4α induction in HEK293 cells (B) and HepG2 cells (C). N=4, mean ± SE. * p<0.05 vs HNF4α-null group. † p<0.05 vs HNF4A-P1–5’UTR-Luc.