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. Author manuscript; available in PMC: 2020 Dec 17.
Published in final edited form as: J Cell Biochem. 2018 Sep 7;120(1):519–532. doi: 10.1002/jcb.27407

Fig. 4. Regulation of HNF4α P2 promoter and HNF4A-AS1 promoter by Pax6.

Fig. 4.

(A) The ChIP-seq data showing the binding of Pax6 to the HNF4A-P2 promoter in the pancreas; (B) Effects of Pax6 and HNF1α on the reporter activity of HNF4A-P2-Luc in HEK293 cells and HepG2 cells. N=4, mean ± SE. * p<0.05 vs control † p<0.05 vs Pax6 or HNF1α single treatment; (C) Effects of Pax6 and HNF4α on the reporter activity of HNF4A-AS1-Pro-Luc in HEK293 cells. N=4, mean ± SE. * p<0.05 vs control. † p<0.05 vs P1-HNF4α group.