Table 2.

Adjusted ORs and 95% CIs for the presence of major renal function decline according to baseline serum lipids levels and AIP.

	Unadjusted		Model 1		Model 2
	OR (95% CI)	p Value	OR (95% CI)	p Value	OR (95% CI)	p Value
Total
TG	1.26 (1.10–1.43)	0.001	1.28 (1.11–1.46)	<0.001	1.23 (1.06–1.43)	0.006
TC	1.03 (0.78–1.36)	0.833	1.03 (0.77–1.39)	0.844	1.02 (0.75–1.38)	0.907
HDL-C	0.79 (0.36–1.75)	0.559	0.78 (0.32–1.92)	0.591	0.85 (0.33–2.19)	0.738
LDL-C	0.79 (0.56–1.12)	0.186	0.76 (0.53–1.10)	0.151	0.78 (0.54–1.14)	0.196
AIP	2.39 (1.14–5.00)	0.021	2.93 (1.27–6.76)	0.012	2.55 (1.01–6.42)	0.047
Men
TG	1.27 (1.10–1.47)	0.001	1.28 (1.10–1.48)	0.001	1.27 (1.08–1.48)	0.003
TC	1.02 (0.70–1.50)	0.922	1.05 (0.71–1.55)	0.804	1.08 (0.72–1.60)	0.714
HDL-C	0.93 (0.25–3.42)	0.914	0.94 (0.26–3.49)	0.930	0.94 (0.23–3.85)	0.933
LDL-C	0.70 (0.43–1.12)	0.137	0.71 (0.44–1.15)	0.161	0.76 (0.46–1.25)	0.283
AIP	3.47 (1.20–10.09)	0.022	3.73 (1.28–10.92)	0.016	3.98 (1.22–12.99)	0.022
Women
TG	1.26 (0.84–1.91)	0.267	1.00 (0.98–1.04)	0.627	1.07 (0.64–1.81)	0.790
TC	1.04 (0.69–1.57)	0.858	0.95 (0.59–1.52)	0.825	1.91 (0.56–1.48)	0.694
HDL-C	0.67 (0.19–2.30)	0.526	0.69 (0.20–2.35)	0.554	0.80 (0.22–2.89)	0.737
LDL-C	0.89 (0.53–1.51)	0.674	0.79 (0.44–1.40)	0.416	0.75 (0.42–1.35)	0.339
AIP	2.04 (0.57–7.29)	0.271	1.83 (0.46–7.29)	0.393	1.29 (0.28–5.95)	0.746

Model 1: adjusted for baseline age and gender.

Model 2: adjusted for covariates in model 1 plus baseline BMI, FPG, uric acid, eGFR, SBP and DBP.

Each variable is expressed per SD and was analyzed in a separate regression model.

SD: standard deviation; CIs: confidence intervals; TC: total cholesterol; TG: triglyceride; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; AIP: atherogenic index of plasma; BMI: body mass index; FBG: fasting blood glucose; eGFR: estimated glomerular filtration rate.