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. 2020 Dec 13;43(1):32–39. doi: 10.1080/0886022X.2020.1853569

Table 3.

Adjusted ORs and 95% CIs for the presence of major renal function decline according to baseline dyslipidaemia and abnormal AIP.

  Unadjusted
Model 1
Model 2
OR (95% CI) p Value OR (95% CI) p Value OR (95% CI) p Value
Total            
 Elevated TG 2.17 (1.17–4.04) 0.014 2.26 (1.18–4.34) 0.014 1.74 (0.86–3.53) 0.123
 Elevated TC 2.23 (0.95–5.23) 0.067 2.26 (0.95–5.39) 0.066 1.98 (0.81–4.83) 0.132
 Reduced HDL-C 1.61 (0.91–2.85) 0.105 1.65 (0.90–3.04) 0.107 1.55 (0.82–2.94) 0.177
 Elevated LDL-C 1.04 (0.32–3.34) 0.953 1.03 (0.32–3.34) 0.963 0.95 (0.29–3.14) 0.933
 Abnormal AIP 2.17 (1.30–3.62) 0.003 2.43 (1.38–4.29) 0.002 2.18 (1.18–4.05) 0.013
Men            
 Elevated TG 2.04 (0.97–4.28) 0.061 2.16 (1.02–4.59) 0.045 1.78 (0.77–4.11) 0.173
 Elevated TC 2.70 (0.93–7.81) 0.067 2.81 (0.97–8.18) 0.058 2.49 (0.82–7.61) 0.109
 Reduced HDL-C 1.35 (0.67–2.74) 0.400 1.35 (0.67–2.74) 0.400 1.34 (0.63–2.87) 0.451
 Elevated LDL-C 1.05 (0.25–4.42) 0.951 1.07 (0.25–4.52) 0.927 1.07 (0.25–4.69) 0.925
 Abnormal AIP 2.09 (1.07–4.11) 0.030 2.15 (1.10–4.22) 0.026 2.16 (1.02–4.55) 0.044
Women            
 Elevated TG 2.93 (0.86–9.94) 0.085 2.70 (0.77–9.52) 0.121 2.02 (0.52–7.88) 0.310
 Elevated TC 1.64 (0.38–7.05) 0.505 1.44 (0.32–6.49) 0.635 1.31 (0.29–6.00) 0.726
 Reduced HDL-C 2.97 (1.00–8.75) 0.048 2.87 (0.97–8.49) 0.057 2.57 (0.83–7.96) 0.101
 Elevated LDL-C 0.99 (0.13–7.46) 0.998 0.86 (0.11–6.62) 0.881 0.75 (0.10–5.92) 0.787
 Abnormal AIP 3.09 (1.23–7.75) 0.016 2.98 (1.13–7.85) 0.028 2.41 (0.82–7.04) 0.107

Model 1: adjusted for baseline age and gender.

Model 2: adjusted for covariates in model 1 plus baseline BMI, FPG, uric acid, eGFR, SBP and DBP.

CIs: confidence intervals; TC: total cholesterol; TG: triglyceride; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; AIP: atherogenic index of plasma; BMI: body mass index; FBG: fasting blood glucose; eGFR: estimated glomerular filtration rate.