Figure 5.

Illustration of mapping into standard brain function for depth electrodes and subdural electrodes. A) Activation map generated on the Montreal Neurological Institute (MNI) brain model using random activation value from all depth electrodes. All the depth electrodes (B-D) are first projected into the right hemisphere for the rendering of activation map for visualization purpose. B/C/D) Sagittal/coronal/axial view of all depth contacts projected into a MNI brain model using volumetric registration method from 23 subjects (Subject 1–22 and 28, n=3158). Contacts are shown with small balls. Different colours represent different anatomical locations, where red indicates gray matter, green indicates white matter, purple indicates hippocampus, blue indicates amygdala, yellow indicates putamen, and gray indicates the remaining regions. E/F/G/H) Different views of all subdural electrodes projected onto a standard brain model (MNI) from 6 subjects (Subject 23–28, n=568). Each subdural electrode is represented with red balls. The subdural electrodes from individual subjects are transformed into the common brain space using volumetric registration method first and then projected onto the surface of the MNI brain model (Sec. 2). I) Activation map generated on the Freesurfer average brain model (FSAverage) using the same activation value with A from all depth electrodes. All the other configurations are the same with A. J/K/L) Sagittal/coronal/axial view of all depth contacts projected into the average brain model using linear space transformation from 23 subjects (Subject 1–22 and 28, n=3158). All the other configurations are the same with B-D. E/F/G/H) Different views of all subdural electrodes projected onto a standard brain model (FSAverage) using surface-based registration from 6 subjects (Subject 23–28, n=568). Electrodes are shown in different colors based on their anatomical locations. Desikan-Killiany atlas is used here for visualization purpose.