Figure 2.
68Ga-prostate-specific membrane antigen positron emission tomography/computed tomography was performed for a 71-year-old male with a history of prostate adenocarcinoma (GS: 4 + 5) underwent prostatectomy 6 years ago. One year after prostatectomy, due to local recurrence, the patient underwent second surgery, external beam radiation therapy and brachytherapy. Due to rising prostate-specific antigen, 68Ga-prostate-specific membrane antigen positron-emission tomography/computed tomography was performed for recurrence evaluation. The scan revealed a mid-esophageal mass with esophageal stenosis and highly increased radiotracer uptake, suggesting a second primary cancer with mediastinal lymph nodes metastases. According to the prior studies, increased prostate-specific membrane antigen expression maybe due to significant neovascularization revealed in gastroesophageal cancers [21,38]