Table 2.
Classification of HSP nephritis severity based on expert opinion from the SHARE initiative
| SEVERITY | DEFINITION |
|---|---|
| Mild nephritis | GFR > 80 mL/min/1.73 m2 and early morning UP:UC ratio of < 250 mg/mmol |
| Moderate nephritis | < 50% crescents on renal biopsy findings and GFR of < 80 mL/min/1.73 m2 or early morning UP:UC ratio of > 250 mg/mmol for at least 4 wk |
| Severe nephritis | > 50% crescents on renal biopsy findings and GFR of < 80 mL/min/1.73 m2 or early morning UP:UC ratio of > 250 mg/mmol for at least 4 wk |
GFR—glomerular filtration rate, HSP—Henoch-Schönlein purpura, SHARE—Single Hub and Access Point for Paediatric Rheumatology in Europe, UC—urine creatinine, UP—urine protein.
Data from Ozen et al.2