| Hsu et al. (2006) |
10 |
Healthy, non-smoking male cyclists and triathletes |
Sildenafil |
At sea level vs simulated high altitude |
At high altitude, sildenafil increased stroke volume, cardiac output and SaO2 |
| Ricard et al. (2005) |
14 |
Healthy males who normally live at sea level |
Sildenafil |
Hypobaric hypoxia at rest and after exercise |
Sildenafil diminishes pulmonary hypertension induced acute exposure to hypobaric hypoxia at rest and after exercise |
| Lalande et al. (2009) |
15 |
Healthy males and females |
Sildenafil |
Sildenafil vs acetazolamide vs placebo all at simulated altitude of 4,300 m |
Sildenafil did not affect breathing efficiency |
| Bates et al. (2011) |
62 |
Healthy males and females |
Sildenafil |
The difference in pulmonary artery systolic pressure at high altitude with sildenafil vs placebo |
There was no significant difference in pulmonary artery systolic pressure at high altitude between the sildenafil and placebo groups |
