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The biodistribution of a targeted nanoformulation against established subcutaneous H1299 tumor, a human non-small cell lung carcinoma cell in nu/nu mice (a) The biodistribution of targeted nano-drug delivery system from nonspecific distribution in 0 h time point to fully accumulated in the tumor in 16 h time points (b) The fluorescent image demonstrated a significant delivery of the nanoparticles in tumor tissue (green region). Reproduced with permission from Ref. [31].
