Figure 1.

FASD 4-Digit Code Ranks for growth, face, central nervous system, and alcohol for 1814 subjects

Bars reflect the proportion of the population receiving Ranks 1–4 for each diagnostic feature. Face Ranks: 1 = no features; 2 = 1 or 2 features; 3 = 2.5 features; 4 = all 3 FAS facial features. Central nervous system (CNS) Ranks: 1 = normal function; 2 = moderate dysfunction; 3 = severe dysfunction; 4 = structural brain abnormalities. Alcohol Ranks: 1 = no prenatal exposure; 2 = unknown exposure; 3 = confirmed exposure to moderate levels; 4 = confirmed exposure to high levels. CNS functional Ranks: subjects with CNS Rank 4 are reclassified in accordance with their functional CNS Rank (1, 2 or 3). CNS functional Rank is presented across all ages (N = 1814). Fifty-two percent of the population was too young (< 8 years old) at the time of diagnosis to confirm or rule out CNS Rank 3 classification, thus the 27% CNS Rank 3 is an underestimate of the true prevalence of severe dysfunction. To portray a more accurate prevalence of severe CNS dysfunction (36%) observed in this alcohol-exposed population the CNS functional Ranks for the 870 subjects aged 8 years and older at the time of diagnosis is presented.