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. Author manuscript; available in PMC: 2020 Dec 17.
Published in final edited form as: Adv Pediatr Res. 2016 Dec 1;3(3):9. doi: 10.12715/apr.2016.3.9

Table 10.

Prevalence of severe CNS dysfunction among 854 subjects that presented with sentinel physical features

Proportion with CNS Rank 3: severe dysfunction
Sentinel physical feature(s) present Growth Ranks 2,3,4 Height and/or weight ≤ 10th % Growth Ranks 3,4 Height and/or weight ≤ 3%

% n % n
None 30 153/514 31 182/594
Growth deficiency only 41* 63/153 47* 34/73
Growth and face 56* 20/36 68* 13/19
Growth, face, and microcephaly 67* 18/27 68* 17/25

Subjects are 8 years of age and older presenting with one or more sentinel physical features of FASD

*

Chi2, P < 0.05 when compared to prevalence of CNS Rank 3 when no features present

Microcephaly is occipital–frontal circumference (OFC) ≤ third percentile. Face includes Face Ranks 3 and 4. Growth reflects the definitions in the two column headings