Fig 2. Urinary concentrations of Na⁺, K⁺, urea and creatinine were reduced in Cx37^-/- compared to WT mice.

Urinary concentrations of (A) Na⁺, (B) K⁺, (C) urea and (D) creatinine were reduced to ~42%, ~62%, ~68% and ~67% in Cx37^-/- compared to WT, respectively. Corrected by urinary creatinine no significant differences were observed for (E) Na⁺, (F) K⁺, (G) urea, PGE2 (H), ATP (I) or AVP (J). Data are expressed as mean ± SEM; n = 12–17. Data were analyzed by Student’s t-test, *P<0.05 versus WT.