Fig 2. NAA concentrations significantly and positively correlated with PMA at scan in widespread white and subcortical gray matter regions in healthy newborns, controlling for sex.

Findings for creatine and choline were weaker but in the same direction and in overlapping brain regions as the findings for NAA. Anatomical reference slices are presented in the top row. Maps indicating the voxels for which at least 75% of the sample had usable data are presented in the bottom row. FDR correction for multiple comparisons was done with FDR at p < .05. Warm colors (red, orange) indicate significant positive associations and cool colors (shades of blue) indicate significant inverse associations, with higher degrees of warmth/coolness corresponding to smaller FDR-corrected p-values as shown in the color bar. SLF, superior longitudinal fasciculus; BG, basal ganglia; Th, thalamus; SFG, superior frontal gyrus; Cd, caudate.