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. 2020 Dec 17;15(12):e0244246. doi: 10.1371/journal.pone.0244246

Table 2. Metabolites highly increased in the triple species culture.

Normalized Log2 Mean Quantity -log10 ANOVA p-value
Metabolite.IDs Medium CT EC SM CT+EC+SM log2 Fold-change
2-Hydroxyisocaproic acid -11.1 -9.4 -8.5 -10.6 -4.9 3.6 13.1
2-Hydroxyisovaleric acid -10.7 -8.9 -8.3 -9.5 -5.2 3.1 4.5
3-Aminoglutaric acid -13.6 -13.6 -11.2 -10.0 -7.4 2.6 1.0
3-Hydroxyisobutyric acid -14.3 -12.6 -14.8 -11.5 -6.9 4.7 2.4
3-Phenyllactic acid -8.7 -5.5 -5.8 -7.8 -3.2 2.3 15.0
4-Hydroxyphenyllactic acid -13.9 -8.7 -8.7 -10.3 -3.8 4.9 1.5
5-Oxoproline -12.5 -12.3 -14.4 -10.6 0.5 11.1 4.6
Dihydrouracil -13.5 -12.9 -11.8 -11.8 -5.7 6.1 2.9
Glutaric acid -10.9 -10.0 -9.2 -12.2 -6.4 2.8 3.4
Glyceraldehyde -13.6 -14.3 -14.0 -14.5 -4.8 8.9 6.4
Indole-3-acetic acid -9.4 -9.4 -9.8 -9.2 -5.8 3.4 8.9
Kynurenic acid -15.3 -10.6 -11.7 -12.0 -7.3 3.3 6.6
Leucine -11.5 -9.3 -13.3 -14.4 0.8 10.1 2.2
N-Acetylserine -10.6 -9.8 -9.7 -9.5 -7.3 2.3 11.6
Threitol -8.2 -7.2 -8.0 -8.4 -5.0 2.1 10.9

*The fold-change is between the CT+EC+SM and the second most intense group.