Table 2. Metabolites highly increased in the triple species culture.
Normalized Log2 Mean Quantity | -log10 ANOVA p-value | ||||||
---|---|---|---|---|---|---|---|
Metabolite.IDs | Medium | CT | EC | SM | CT+EC+SM | log2 Fold-change | |
2-Hydroxyisocaproic acid | -11.1 | -9.4 | -8.5 | -10.6 | -4.9 | 3.6 | 13.1 |
2-Hydroxyisovaleric acid | -10.7 | -8.9 | -8.3 | -9.5 | -5.2 | 3.1 | 4.5 |
3-Aminoglutaric acid | -13.6 | -13.6 | -11.2 | -10.0 | -7.4 | 2.6 | 1.0 |
3-Hydroxyisobutyric acid | -14.3 | -12.6 | -14.8 | -11.5 | -6.9 | 4.7 | 2.4 |
3-Phenyllactic acid | -8.7 | -5.5 | -5.8 | -7.8 | -3.2 | 2.3 | 15.0 |
4-Hydroxyphenyllactic acid | -13.9 | -8.7 | -8.7 | -10.3 | -3.8 | 4.9 | 1.5 |
5-Oxoproline | -12.5 | -12.3 | -14.4 | -10.6 | 0.5 | 11.1 | 4.6 |
Dihydrouracil | -13.5 | -12.9 | -11.8 | -11.8 | -5.7 | 6.1 | 2.9 |
Glutaric acid | -10.9 | -10.0 | -9.2 | -12.2 | -6.4 | 2.8 | 3.4 |
Glyceraldehyde | -13.6 | -14.3 | -14.0 | -14.5 | -4.8 | 8.9 | 6.4 |
Indole-3-acetic acid | -9.4 | -9.4 | -9.8 | -9.2 | -5.8 | 3.4 | 8.9 |
Kynurenic acid | -15.3 | -10.6 | -11.7 | -12.0 | -7.3 | 3.3 | 6.6 |
Leucine | -11.5 | -9.3 | -13.3 | -14.4 | 0.8 | 10.1 | 2.2 |
N-Acetylserine | -10.6 | -9.8 | -9.7 | -9.5 | -7.3 | 2.3 | 11.6 |
Threitol | -8.2 | -7.2 | -8.0 | -8.4 | -5.0 | 2.1 | 10.9 |
*The fold-change is between the CT+EC+SM and the second most intense group.