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. 2020 Dec 17;15(12):e0243805. doi: 10.1371/journal.pone.0243805

Table 1. Socio-demographic and clinical characteristics of the study participants and controls.

Study group Study group Controls
HNC TMD HNC + TMD
Mean (SD) p-value Mean (SD) p-value
Median (Range) Median (Range)
Age (years) 67 (7.5) 45 (16.7) < 0.0001 62 (13.9) 62 (13.1) 0.56
67 (49–84) 45 (16–71) 65 (16–84) 65 (16–88)
MIO (mm) 40.1 (10.3) 36.3 (8.1) 0.047 39.2 (9.9) 52.5 (6.8)
36 (20–50) 40 (16–58) 52 (37–73) < 0.0001
41 (16–58)
Gender n (%) n (%)
Male 68 (76) 4 (15) 72 (62) 72 (62)
Female 22 (24) 22 (85) < 0.001 44 (38) 44 (38) 1.00
Marital status
Single 67 (74) 21 (81) 88 (76) 89 (77)
Married/Cohabitant 23 (26) 5 (19) 0.70 28 (24) 26 (23) 0.91
Education level
Elementary school 21 (24) 3 (12) 24 (21) 15 (13)
High school 29 (33) 9 (38) 38 (34) 40 (35)
University 38 (43) 12 (50) 0.31 50 (45) 59 (52) 0.12
Occupational status
Working 24 (27) 12 (46) 36 (31) 50 (43)
Retired 64 (71) 7 (27) 71 (61) 63 (54)
Studying 0 (0) 5 (19) 5 (4) 3 (3)
Other 2 (2) 2 (8) < 0.001 4 (4) 0 (0) 0.064
Smoking
Never smoked 39 (43) 16 (61) 55 (47) 63 (54)
Stopped smoking 47 (52) 8 (31) 55 (47) 46 (40)
Current smoker 4 (4) 2 (8) 0.26 6 (6) 7 (6) 0.44
Cancer location
Tonsil 45 (50)
Base of tongue 20 (23)
Tumour colli 8 (9)
Tongue 3 (3)
Oropharynx 3 (3)
Other 11 (12)
Reason for TMD
Disc problems 14 (54)
Arthritis 6 (23)
Muscular 6 (23)

HNC = Head and neck cancer, TMD = temporomandibular disorders, MIO = Maximum incisal opening.