TABLE 1.
Normonatremic Patients Compared With Patients With ICU-Acquired Hypernatremia
| Variables | Medical Information Mart for Intensive Care III (n = 23,445) | Electronic ICU (n = 88,160) | ||
|---|---|---|---|---|
| Normonatremia (n = 21,273) | Hypernatremia (n = 2,172) | Normonatremic (n = 82,370) | Hypernatremic (n = 5,790) | |
| Age, median (IQR) | 63 (51–75) | 69 (56–78) | 65 (53–75) | 67 (56–77) |
| Male, n (%) | 12,260 (58) | 1,302 (60) | 44,526 (54) | 3,282 (57) |
| Acute Physiology Score III, median (IQR) | 35 (26–45) | 48 (36–63) | — | — |
| Acute Physiology and Chronic Health Evaluation IV, median (IQR) | — | — | 50 (37–65) | 71 (55–91) |
| Number of samples, median (IQR) | 6 (4–9) | 21 (13–32) | 4 (3–7) | 14 (9–22) |
| Sodium (mmol/L), mean ± sd | 139 ± 3.1 | 143 ± 4.7 | 139 ± 3.1 | 144 ± 3.1 |
| Glucose (mg/dL), mean ± sd | 130 ± 57 | 135 ± 61 | 133 ± 57 | 147 ± 57 |
| Length of stay (d), median (IQR) | 6.0 (3.9–9.4) | 15.1 (9.7–24.0) | 3.3 (1.8–5.5) | 9.8 (6.1–15.4) |
| Ward, n (%) | ||||
| Cardiothoracic ICUa | 7,753 (36) | 433 (20) | 18,832 (23) | 969 (17) |
| General ICUb | 13,520 (64) | 1,739 (80) | 57,715 (70) | 4,254 (73) |
| Neurologic ICUc | — | — | 5,823 (7) | 567 (10) |
| Administration of hypertonic saline or sodium bicarbonated, n (%) | 1,201 (6) | 395 (18) | — | — |
| In-hospital mortality, n (%) | 4,170 (20) | 912 (42) | 4,647 (6) | 1,296 (22) |
IQR = interquartile range.
aCardiothoracic ICU includes cardiac surgery recovery unit, coronary care unit, cardiac ICU, cardiac surgical ICU, cardiothoracic ICU, and coronary-cardiothoracic ICU.
bGeneral ICU includes medical ICU, surgical ICU, trauma/surgical ICU, and medical-surgical ICU.
cThere is not a neurologic ICU in Medical Information Mart for Intensive Care III.
dThis information was not available in electronic ICU.
Dash indicates when data is not available in the specific database.