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. 2020 Dec 16;2(12):e0299. doi: 10.1097/CCE.0000000000000299

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Copyright © 2020 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the Society of Critical Care Medicine.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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Figure 2. — Calibration of model to experimental data. A, Respiratory system elastance versus time in mice following recruitment maneuvers given at t = 0 at three different positive end-expiratory pressure (PEEP) levels (adapted from a previous study [10] with permission from the American Physiologic Society). Open symbols: baseline conditions; closed symbols: lung injury; circles: PEEP = 1 cm H₂O; squares: PEEP = 3 cm H₂O; triangles: PEEP = 6 cm H₂O. B, Elastance profiles simulated using the model. Solid lines: baseline conditions; dashed lines: lung injury.