TABLE 2.
Adjusted outcomes by concurrent surgery type compared with HAIP placement alone
| Death and serious morbidity | n (%) | Adjusted odds ratio (95% CI) |
P value |
|---|---|---|---|
| HAIP alone (n = 75) | 8 (10.7) | 1.00 (REF) | - |
| Minor liver (n = 167) | 32 (19.2) | 2.20 (0.91–5.29) | 0.080 |
| Colorectal (n = 77) | 17 (22.1) | 2.21 (0.83–5.86) | 0.111 |
| Colorectal plus minor liver (n = 69) | 16 (23.2) | 2.85 (1.05–7.76) | 0.040 |
| Major liver (n = 67) | 19 (28.4) | 3.79 (1.44–9.99) | 0.007 |
| Colorectal and major liver (n = 12) | 5 (41.7) | 6.77 (1.59–28.85) | 0.010 |
| Wound complications | n (%) | Adjusted odds ratio (95% CI) |
P value |
| HAIP alone (n = 75) | 2 (2.7) | 1.00 (REF) | - |
| Minor liver (n = 167) | 17 (10.2) | 4.39 (0.94–20.57) | 0.061 |
| Colorectal (n = 77) | 13 (17.9) | 6.13 (1.24–30.17) | 0.026 |
| Colorectal plus minor liver (n = 69) | 10 (14.5) | 6.86 (1.32–35.50) | 0.022 |
| Major liver (n = 67) | 10 (14.9) | 7.58 (1.49–38.59) | 0.015 |
| Colorectal and major liver (n = 12) | 4 (33.3) | 18.94 (2.68–134.00) | 0.003 |
| Infectious complications | n (%) | Adjusted odds ratio (95% CI) |
P value |
| HAIP alone (n = 75) | 3 (4.0) | 1.00 (REF) | - |
| Minor liver (n = 167) | 19 (11.4) | 3.32 (0.91–12.05) | 0.069 |
| Colorectal (n = 77) | 12 (15.6) | 4.07 (1.03–16.03) | 0.045 |
| Colorectal plus minor liver (n = 69) | 13 (18.8) | 6.66 (1.67–26.60) | 0.007 |
| Major liver (n = 67) | 11 (16.4) | 5.34 (1.35–21.14) | 0.017 |
| Colorectal and major liver (n = 12) | 4 (33.3) | 13.45 (2.34–77.26) | 0.004 |
| Length of stay (days) | Median (IQR) | Adjusted incidence rate ratio (95% CI) |
P value |
| HAIP alone (n = 75) | 5 (4–7) | 1.00 (REF) | - |
| Minor liver (n = 167) | 6 (5–7) | 1.29 (1.15–1.46) | < 0.001 |
| Colorectal (n = 77) | 7 (6–9) | 2.00 (1.76–2.28) | < 0.001 |
| Colorectal plus minor liver (n = 69) | 7 (6–10) | 1.81 (1.58–2.08) | < 0.001 |
| Major liver (n = 67) | 7 (6–10) | 1.86 (1.63–2.12) | < 0.001 |
| Colorectal and major liver (n = 12) | 10 (7–15) | 2.94 (2.44–3.54) | < 0.001 |
| Operative time (minutes) | Mean (SD) | Mean difference β (95% CI) |
P value |
| HAIP alone (n = 75) | 186.6 (58.9) | 0.0 (REF) | - |
| Minor liver (n = 167) | 252.4 (83.2) | 62.5 (37.3–87.7) | < 0.001 |
| Colorectal (n = 77) | 326.4 (120.8) | 130.5 (100.8–160.1) | < 0.001 |
| Colorectal plus minor liver (n = 69) | 336.2 (84.9) | 143.4 (112.5–174.4) | < 0.001 |
| Major liver (n = 67) | 307.7 (94.3) | 122.5 (92.0–152.9) | < 0.001 |
| Colorectal and major liver (n = 12) | 398.4 (94.8) | 209.4 (154.0–264.8) | < 0.001 |
HAIP: Hepatic artery infusion pump; CI: confidence interval; IQR: interquartile range; SD: standard deviation