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. 2020 Dec 7;16(12):e1009229. doi: 10.1371/journal.pgen.1009229

Fig 4. Gene expression in orthologous versus non-orthologous TADs.

Fig 4

A) Genes within orthologous TADs are expressed at significantly reduced levels compared to non-orthologous TADs, consistent with Polycomb-repression (Wilcoxon test p = 6.7e–05) B) Orthologous TADs contain slightly fewer differentially-expressed (DE) genes compared to non-orthologous TADs (9.1% versus 10.5%), however this difference is not statistically significant (Fisher’s Exact Test p = 0.151). Differentially-expressed genes were identified using the DESeq2 R software package [52].