Table 1. The incidence of ALL in 1990/2017 and temporal trends.
| 1990 | 2017 | 1990-2017 | |||
| Incident cases No *103 (95% UI) | ASIR /100,000 No. (95% UI) | Incident cases No *103 (95% UI) | ASIR /100,000 No. (95% UI) | EAPC No. (95% CI) | |
| Overall | 49.07 (41.00~67.32) | 0.89 (0.76~1.20) | 64.19 (56.39~70.40) | 0.85 (0.75~0.94) | -0.08 (-0.15~-0.02) |
| Sex | |||||
| Male | 29.77 (22.72~38.73) | 1.08 (0.85~1.37) | 37.58 (32.24~41.52) | 1.00 (0.86~1.11) | -0.23 (-0.3~-0.16) |
| Female | 19.30 (14.81~32.54) | 0.71 (0.55~1.16) | 26.62 (21.80~30.33) | 0.71 (0.58~0.82) | 0.15 (0.08~0.22) |
| Socio-demographic factor | |||||
| High SDI | 8.45 (8.27~8.69) | 0.89 (0.86~0.91) | 7.13 (6.92~7.43) | 0.55 (0.53~0.57) | -1.89 (-1.94~-1.83) |
| High-middle SDI | 11.38 (10.10~13.63) | 1.03 (0.92~1.24) | 12.94 (10.76~13.90) | 0.97 (0.80~1.05) | -0.08 (-0.20~0.05) |
| Middle SDI | 14.49 (12.34~18.94) | 0.93 (0.80~1.19) | 22.06 (18.45~23.71) | 1.10 (0.93~1.18) | 0.82 (0.73~0.90) |
| Low-middle SDI | 8.30 (6.21~12.78) | 0.72 (0.56~1.05) | 12.70 (11.06~15.18) | 0.74 (0.65~0.89) | 0.23 (0.13~0.34) |
| Low SDI | 6.24 (3.45~13.67) | 0.74 (0.45~1.45) | 9.09 (7.79~11.24) | 0.65 (0.56~0.80) | -0.52 (-0.6~-0.43) |
| Region | |||||
| Andean Latin America | 0.49 (0.39~0.67) | 1.15 (0.94~1.53) | 0.97 (0.73~1.13) | 1.58 (1.20~1.83) | 1.51 (1.37~1.64) |
| Australasia | 0.33 (0.31~0.34) | 1.55 (1.48~1.62) | 0.32 (0.29~0.36) | 0.93 (0.84~1.04) | -2.33 (-2.53~-2.13) |
| Caribbean | 0.37 (0.30~0.57) | 1.00 (0.82~1.50) | 0.36 (0.31~0.41) | 0.81 (0.69~1.06) | -0.81 (-0.92~-0.69) |
| Central Asia | 0.73 (0.66~0.82) | 0.97 (0.89~1.08) | 0.77 (0.69~0.85) | 0.88 (0.79~0.96) | -0.13 (-0.24~-0.01) |
| Central Europe | 1.34 (1.26~1.44) | 1.10 (1.03~1.19) | 0.88 (0.83~0.93) | 0.68 (0.63~0.72) | -1.69 (-1.79~-1.59) |
| Central Latin America | 2.99 (2.86~3.31) | 1.77 (1.71~1.92) | 5.31 (5.06~5.70) | 2.12 (2.02~2.27) | 0.80 (0.67~0.94) |
| Central Sub-Saharan Africa | 0.22 (0.09~0.56) | 0.32 (0.17~0.70) | 0.49 (0.31~0.86) | 0.35 (0.25~0.56) | 0.36 (0.31~0.42) |
| East Asia | 9.06 (7.03~13.64) | 0.73 (0.57~1.11) | 13.68 (9.60~15.10) | 0.96 (0.68~1.07) | 1.29 (0.85~1.73) |
| Eastern Europe | 3.26 (2.95~3.54) | 1.50 (1.34~1.61) | 2.32 (2.21~2.46) | 1.00 (0.94~1.07) | -1.61 (-1.71~-1.50) |
| Eastern Sub-Saharan Africa | 1.86 (1.06~3.43) | 0.73 (0.45~1.25) | 3.69 (2.76~5.15) | 0.77 (0.59~1.05) | 0.002 (0.15~0.31) |
| High-income Asia Pacific | 1.51 (1.44~1.59) | 0.91 (0.86~0.95) | 1.16 (1.09~1.22) | 0.50 (0.46~0.53) | -2.27 (-2.39~-2.16) |
| High-income North America | 2.17 (2.12~2.22) | 0.78 (0.76~0.80) | 2.13 (2.02~2.25) | 0.54 (0.51~0.57) | -1.47 (-1.56~-1.39) |
| North Africa and Middle East | 3.28 (2.33~5.33) | 0.87 (0.62~1.35) | 4.28 (3.51~5.07) | 0.72 (0.59~0.85) | -0.48 (-0.60~-0.36) |
| Oceania | 0.04 (0.02~0.06) | 0.56 (0.36~0.91) | 0.07 (0.04~0.11) | 0.52 (0.35~0.82) | -0.21 (-0.25~-0.16) |
| South Asia | 9.76 (6.69~17.14) | 0.78 (0.56~1.29) | 13.01 (10.86~15.03) | 0.74 (0.61~0.85) | -0.17 (-0.32~-0.02) |
| Southeast Asia | 4.88 (3.65~7.61) | 1.06 (0.83~1.56) | 8.03 (6.84~8.93) | 1.28 (1.09~1.43) | 0.83 (0.63~1.03) |
| Southern Latin America | 0.50 (0.46~0.54) | 1.00 (0.92~1.07) | 0.58 (0.53~0.64) | 0.91 (0.83~1.00) | -0.23 (-0.32~-0.14) |
| Southern Sub-Saharan Africa | 0.08 (0.06~0.10) | 0.16 (0.12~0.18) | 0.12 (0.08~0.15) | 0.16 (0.11~0.19) | -0.10 (-0.47~0.27) |
| Tropical Latin America | 1.73 (1.58~1.85) | 1.06 (0.98~1.13) | 1.85 (1.76~1.97) | 0.90 (0.85~0.95) | -0.37 (-0.57~-0.17) |
| Western Europe | 3.51 (3.43~3.60) | 0.91 (0.89~0.94) | 2.73 (2.60~2.87) | 0.54 (0.51~0.57) | -2.14 (-2.28~-2.01) |
| Western Sub-Saharan Africa | 0.96 (0.65~1.44) | 0.45 (0.34~0.61) | 1.45 (1.13~2.04) | 0.35 (0.27~0.46) | -1.36 (-1.62~-1.11) |
Note: ASIR: age-standardized incidence rate