Table 2. Univariate and multivariate analysis of factors associated with overall survival in cervical cancer patients^a.

Variables	Subset	HR b (95%CI)	P-value
Univariate analysis
Age, years	>35 vs. ≤35	0.6(0.2-1.6)	0.330
FIGO stage	IIA vs.IB1/IB2	1.6(0.6-4.4)	0.318
Greatest tumor dimension, cm	>4 vs. ≤4	2.1(0.8-5.7)	0.141
Lymphovascular space invasion	Yes or no	1.8(0.4-8.2)	0.404
Depth of cervical invasion	≥66% vs. <66%	11.4(1.5-86)	0.019 a
Uterine corpus invasion	Yes or no	1.7(0.9-3.2)	0.102
Pelvic lymph node metastasis	Yes or no	1.5(0.5-4.2)	0.428
Differentiation	poor vs. well/moderate	6.5(1.5-28.4)	0.013 a
F. nucleatum level	high vs. low	4.9(1.4-17.4)	0.013 a
Multivariate analysis
Differentiation	poor vs. well/moderate	6.1(1.2-29.7)	0.023 a
Lymphovascular space invasion	Yes or no	7.1(1.0-50.1)	0.047 a
Depth of cervical invasion	≥66% vs. <66%	16.7(1.9-148)	0.011 a

^aCox proportional hazards regression model. Variables used in multivariate analysis were adopted by univariate analysis. Significant p values (< 0.05) are shown in bold font.

^bHR > 1, risk for death increased; HR < 1, risk for death decreased.

Abbreviations: HR, hazard ratio; CI, confidence interval; NA, not applicable.