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PMOs inhibited the metastasis of osteosarcoma. K7M2 WT cells were injected into the tail veins of mice in the control, IMO and PMO groups, and metastatic nodules in the lungs were quantified. (A) H&E staining of lung tissues from each group. Representative images are shown. (B) The number of metastatic nodules was counted. ****, P<0.0001 in an unpaired two-tailed t test.
