. 2020 Nov 10;12(22):23029–23046. doi: 10.18632/aging.104049

Table 2. Logistic regression model: risk factors for endometrial cancer.

Variables	OR	95%CI	P^a	OR	95%CI	P^b
Age
≤55	1(R)	-	0.001	1(R)	-	0.41
>55	33.366	4.358-255.432		4.49	0.126-160.285
BMI
<25	1(R)	-	0.004	1(R)	-	0.17
≥25	6.48	1.825-23.014		11.363	0.354-365.035
Parity
≤1	1(R)	-	0.002	1(R)	-	0.148
>1	3.777	1.642-8.688		0.22	0.028-1.712
Gravidity
≤2		-	<0.001		-	0.777
>2	13.667	3.877-48.181		1.571	0.069-35.596
Pausimenia
No	1(R)	-	<0.001	1(R)	-	0.237
Yes	11.1	3.149-39.124		4.703	0.362-61.067
Hypertension
No	1(R)	-	0.003	1(R)	-	0.573
Yes	9.99	2.234-44.677		2.93	0.07-122.652
Hyperlipaemia
No	1(R)	-	0.003	1(R)	-	0.47
Yes	9.99	2.234-44.677		0.218	0.003-13.557
Diabetes mellitus
No	1(R)	-	0.013	1(R)	-	0.789
Yes	13.333	1.717-103.56		0.603	0.015-24.505
CA153
≤31.3	1(R)	-	0.017	1(R)	-	0.835
>31.3	1.122	1.021-1.233		1.007	0.131-6.682
CEA
≤5	1(R)	-	0.02	1(R)	-	0.925
>5	2.055	1.12-3.771		0.955	0.944-1.073
CA125
≤35	1(R)	-	0.74	-	-	-
>35	1.001	0.997-1.005		-	-
CA199
≤37	1(R)	-	0.347	-	-	-
>37	1.004	0.996-1.012		-	-
AFP
≤8.78	1(R)	-	0.309	-	-	-
>8.78	1.237	0.821-1.864		-	-
PPARγ^c
>0.019	1(R)	-	0.001	1(R)	-	0.107
≤0.019	0.243	0.106-0.556		0.034	0.001-2.075
ERRα^d
≤0.0041	1(R)	-	<0.001	1(R)	-	0.14
>0.0041	5.976	2.551-13.999		16.66	0.397-699.901
PPARγ/ERRα^e
>1.86	1(R)	-	<0.001	1(R)	-	0.018
≤1.86	32	8.896-115.107		14.847	1.6-137.748

^a The results were evaluated using univariate analysis.^bThe results were evaluated using logistic regression analysis. ^cThe mRNA expression of PPARγ was quantified using 2^-ΔCT method. ^d The mRNA expression of ERRα was quantified using 2^-ΔCT method. ^ePPARγ/ERRα was quantified the ratio of mRNA expression of PPARγ and ERRα. FBG, fasting blood glucose.