Table 4. Clinicopathological characteristics of COAD patients from the TCGA database.

Characteristics	Patients
	Total (N = 287)		Training cohort (N = 143)		Validation cohort (N = 144)
	No	%	No	%	No	%
Age
≤64	130	45.30	58	40.56	72	50
>64	157	54.70	85	59.44	72	50
Histological type
Colon Adenocarcinoma	246	85.71	119	83.22	127	88.19
Colon Mucinous Adenocarcinoma	38	13.24	22	15.38	16	11.11
Unknown	3	1.05	2	1.40	1	0.70
Pathologic M
M0	195	67.94	102	71.33	93	64.58
M1	40	13.94	21	14.69	19	13.19
MX	49	17.07	19	13.29	30	20.83
Unknown	3	1.05	1	0.07	2	1.39
Pathologic N
N0	166	57.84	73	51.05	93	64.58
N1	73	25.44	46	32.17	27	18.75
N2	48	16.72	24	1.40	24	16.67
Pathologic T
T1	7	2.44	2	1.39	5	3.47
T2	42	14.63	17	11.89	25	17.36
T3	199	69.34	105	73.43	94	65.28
T4	38	13.24	19	13.29	19	13.19
Unknown	1	0.35	0	0	1	0.70
Gender
Female	134	46.69	70	48.95	64	44.44
Male	153	53.31	73	51.05	80	55.56
Race
American Indian or Alaska Native	1	0.35	1	0.70	0	0
Asian	11	3.83	4	2.80	7	4.86
Black or African American	57	19.86	20	13.98	37	25.70
White	201	70.04	108	75.52	93	64.58
Unknown	17	5.92	10	7.00	7	4.86
Tumor stage
Stage I	43	14.98	16	11.19	27	18.75
Stage II	110	38.33	52	36.36	58	40.28
Stage III	84	29.27	51	14.69	33	22.92
Stage IV	40	13.94	21	2.10	19	13.19
Unknown	10	3.48	3	27.27	7	4.86
Lymphatic invasion
Yes	76	26.48	39	27.27	37	25.69
No	175	60.98	88	61.54	87	60.42
Unknown	36	12.54	16	11.19	20	13.89
Primary lymph node presentation assessment
Yes	265	92.33	134	93.70	131	90.97
No	14	4.88	5	3.50	9	6.25
Unknown	8	2.79	4	2.80	4	2.78
Vital status
Alive	218	75.96	107	74.83	111	77.08
Dead	69	24.04	36	25.17	33	22.92
Longest dimension
≥2	43	14.98	27	18.88	16	11.11
<2	175	60.98	90	62.94	85	59.03
Unknown	69	24.04	26	18.18	43	29.86
Sample type
Metastatic	1	0.35	0	0	1	0.69
Primary Tumor	285	99.30	142	99.30	143	99.31
Recurrent Tumor	1	0.35	1	0.70	0	0
Lymph node examined count
≥12	226	78.75	117	81.82	109	75.70
<12	42	14.63	19	13.28	23	15.97
Unknown	19	6.62	7	4.90	12	8.33