Table 3.
Association between osteopenia and RANKL SNP.
| SNP | Control N (%) | Osteopenia N (%) | Osteopenia | |
|---|---|---|---|---|
| OR (95% confidence interval) | p value | |||
| rs2277438 | ||||
| GG | 10 (5.0) | 70 (48.3) | 20.56 (9.82–43.06) | <0.001 |
| AG | 49 (24.5) | 27 (18.6) | 1.62 (0.91–2.87) | 0.09 |
| AA | 141 (70.2) | 48 (33.1) | 1 | |
| G | 69 (17.3) | 167 (57.5) | 4.54 (3.18–6.49) | <0.001 |
| A | 231 (82.7) | 123 (42.4) | 1 | |
| rs9533156 | ||||
| TT | 92 (36.9) | 79 (31.7) | 1 | |
| TC | 82 (31.3) | 97 (37.0) | 1.38 (0.91–2.10) | 0.14 |
| CC | 42 (38.5) | 39 (35.8) | 1.08 (0.64–1.84) | 0.77 |
| T | 266 (61.6) | 255 (59.3) | 1 | |
| C | 166 (38.4) | 175 (40.7) | 1.10 (0.84–1.44) | 0.50 |
Note: data are presented as frequencies N (%) and OR (95% CI). p value <0.05 is considered significant.