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. 2020 Dec 3;8(12):e18352. doi: 10.2196/18352

Table 2.

Comparison of sepsis-2 and sepsis-3 criteria.

Stage Sepsis-2 criteria (SIRSa) Sepsis-3 criteria (qSOFAb)
Sepsis Suspected or confirmed infection + SIRS Suspected or confirmed infection + qSOFA score ≥2
Severe sepsis Sepsis + organ dysfunction (lab markers, including hypoxia, hypotension, elevated lactate) Category removed
Septic shock Severe sepsis + persistent hypotension (after adequate fluid resuscitation) Sepsis + vasopressors to maintain mean arterial pressure ≥65 mmHg + serum lactate level >2 mmol/L

aSIRS: systemic inflammatory response syndrome.

bqSOFA: quick Sequential Organ Failure Assessment.