Table 2.
Comparison of sepsis-2 and sepsis-3 criteria.
| Stage | Sepsis-2 criteria (SIRSa) | Sepsis-3 criteria (qSOFAb) |
| Sepsis | Suspected or confirmed infection + SIRS | Suspected or confirmed infection + qSOFA score ≥2 |
| Severe sepsis | Sepsis + organ dysfunction (lab markers, including hypoxia, hypotension, elevated lactate) | Category removed |
| Septic shock | Severe sepsis + persistent hypotension (after adequate fluid resuscitation) | Sepsis + vasopressors to maintain mean arterial pressure ≥65 mmHg + serum lactate level >2 mmol/L |
aSIRS: systemic inflammatory response syndrome.
bqSOFA: quick Sequential Organ Failure Assessment.