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. 2020 Dec 17;4(4):e403–e412. doi: 10.1055/s-0040-1721706

Fig. 3.

Fig. 3

Diagrammatic illustration of host-viral interactions of some of the hub genes that came out from our network-based meta-analysis. The host–virus interactions participation of some of our hub genes is suggestive that these pathological conditions strengthens a favorable environment for virus and further aids in aggravating its viral load and deterioration of patients. ACE2, angiotensin-converting enzyme 2; CDK1, cyclin dependent kinase 1; DHX9, DExH-box helicase 9; IKK, i-κ-kinase; KAT2B, lysine acetyltransferase 2B; NF-κβ, nuclear factor kappa B; P21/CDK, P21/cyclin-dependent kinase; PSMB2, proteasome β subunits 2 family; PSME3, proteasome activator complex subunit 3; RBX1, RING-box protein 1; RELA, REL-associated protein; SARS-CoV-2, severe acute respiratory syndrome-coronavirus-2; TLR2, toll-like receptor 2; TMPRSS2, transmembrane serine protease 2; TP53, tumor protein 53; WRAP53, WD repeat containing antisense to TP53.