Table 1.

Infused CB and haplo-identical graft characteristics.

Baseline Graft Characteristics	Value
Cord Blood Units (n = 156 infused units)
Infused TNC dose × 107/kg/unit, median (range)	2.3 (1.0–5.7)
Infused viable CD34+ dose × 105/kg/unit, median (range)	1.1 (0.1–3.1)
Infused viable CD3+ dose × 106/kg/unit, median (range)	2.9 (0.3–8.0)
Unit-recipient HLA-A, -B antigen, -DR allele match, N (%)
4/6	122 (78%)
5/6	31(20%)
6/6	3 (2%)
Unit-recipient 8-allele HLA match, N (%)
2–3/8	15 (10%)
4/8	44 (28%)
5/8	68 (44%)
6–7/8	29 (19%)
Haplo-CD34+ Grafts (n = 78)
Relationship to pt, N (%)
Child	36 (46%)
Sibling	24 (31%)
Parent	10 (13%)
Extended family	8 (10%)
Cryopreserved, N (%)	12 (15%)
Infused CD34+ dose × 106/kg, median (range)	5.2 (1.1–16.8)
Infused CD3+ dose × 103/kg, median (range)	1.6 (0.3–13.7)*
Haplo-CD34+-recipient 8-allele HLA match, N (%)
4/8	61 (78%)
5–6/8	16 (21%)
7/8	1 (1%)

^*A single haplo-identical graft had a CD3+ cell dose above the 8 × 10³/kg cap due to inadequate purity of CD34+ selection. To avoid compromising the CD34+ dose, further T-cell depletion was not performed.