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The roles of inflammatory factors and inflammatory signaling pathways in aberrant scar formation. Red arrows, Positive effects; Green arrows, Negative effects; TLRs, Toll-Like Receptors; DAMPs, damage associated molecular patterns; NF-κB, Nuclear factor kappa B (NF-κB); STAT-3, Signal transducer and activator of transcription 3; FAK, Focal adhesion kinase; IL-6, Interleukin-6; IL-8, Interleukin-8; MCP-1, Monocyte chemoattractant protein-1; CXCL12, Chemokines ligand 12.
