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. 2020 Dec 4;11:602485. doi: 10.3389/fgene.2020.602485

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Copyright © 2020 Xu, Liu, Liu, Xu, Cheng, Shou, Tong, Liu, Zhou, Xiao, Xiong, Yuan, Chen, Liu, Yang, Liang, Chen and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Transcriptome profiles of m⁶A RNA methylation regulators in prostate adenocarcinoma. (A,B) The differential expression of m⁶A related genes between 499 tumorous tissues and 52 normal tissues in TCGA-PRAD cohort. (C) The correlation of the m⁶A regulatory genes. (D) Protein-protein interaction (PPI) network of m⁶A regulatory genes. Elements not connected to other genes are hidden. (E) PPI network of top 10 pivotal genes from all m⁶A regulatory genes obtained by CytoHubba plugin of Cytoscape.