Table. Patient Characteristics at Baseline, Stratified by PED Status at Month 1a.
| Characteristic | No. (%) | |
|---|---|---|
| PED present at month 1 (n = 378) | PED absent at month 1 (n = 208) | |
| Age, mean (SD), y | 78.9 (8.0) | 80.3 (7.6) |
| Sex | ||
| Female | 233 (61.6) | 138 (66.3) |
| Male | 145 (38.4) | 70 (33.7) |
| Race/ethnicity | ||
| American Indian or Alaska Native | 1 (0.3) | 0 |
| Asian | 7 (1.9) | 1 (0.5) |
| Black or African American | 2 (0.5) | 0 |
| Multiracial | 0 | 1 (0.5) |
| Native Hawaiian or other Pacific Islander | 1 (0.3) | 1 (0.5) |
| White | 363 (97.1) | 203 (98.5) |
| Ethnicity | ||
| Hispanic or Latino | 10 (2.6) | 9 (4.3) |
| Not Hispanic or Latino | 368 (97.4) | 199 (95.7) |
| PED height, mean (SD), μm | 319.9 (183.5) | 206.0 (104.9) |
| Presence of drusen | ||
| No | 368 (98.7) | 202 (98.5) |
| Yes | 5 (1.3) | 3 (1.5) |
| Soft drusen | ||
| No | 45 (12.1) | 20 (9.8) |
| Yes | 328 (87.9) | 185 (90.2) |
| Hard drusen | ||
| No | 9 (2.4) | 4 (2.0) |
| Yes | 364 (97.6) | 201 (98.0) |
| No. of intermediate/large drusen | ||
| 0-5 | 199 (53.2) | 98 (48.5) |
| ≥6 | 175 (46.8) | 104 (51.5) |
| Time from diagnosis to first RBZ injection, mean (SD), d | 40.6 (252.2) | 26.0 (61.5) |
| Subretinal fluid thickness, mean (SD), μm | 155.7 (108.8) | 111.2 (91.9) |
| Central retinal/lesion thickness, mean (SD), μm | 417.1 (138.2) | 432.1 (132.3) |
| Central subfield thickness, mean (SD), μm | 358.1 (112.3) | 372.1 (96.5) |
| CNV thickness, mean (SD), μm | 153.1 (104.4) | 148.9 (83.5) |
| Central foveal thickness, mean (SD), μm | 324.2 (133.5) | 337.3 (127.0) |
Abbreviations: CNV, choroidal neovascularization; PED, pigment epithelial detachment; RBZ, ranibizumab.
a
Data limited to patients with PEDs present at baseline.