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. Author manuscript; available in PMC: 2020 Dec 18.
Published in final edited form as: Nat Chem Biol. 2020 Nov 16;16(12):1321–1330. doi: 10.1038/s41589-020-00688-0

Table 1.

Overall leaflet PL class compositions of RBC PMs. Shown are mol% of various classes per leaflet.

Leaflet composition
[mol% of PL in leaflet]
Group Year Technique Leaflet SM PC PE PI PS
Verkleij et al10 1973 enzyme digestion* + TLC Human exo- 41% 48% 11% 0% 0%
endo- 10% 17% 49% 0% 24%
Renooij16 1974 enzyme digestion* + TLC Rat exo- 27% 59% 11%  2% 
endo- 0% 31% 39%   29%
Rawyler et al17 1985 PLA digestion + PC transfer protein + fluorescamine labeling + TLC Mouse exo- 33% 45% 16% 6% 0%
endo- 3% 48% 29% 4% 16%
Van der Schaft et al18 1987 PLA digestion + PC transfer protein + fluorescamine labeling + TLC Monkey exo- 42% 53% 5% 0% 0%
endo- 4% 34% 39% 8% 15%
Lorent et al1 2020 enzyme digestion + shotgun lipidomics Human exo- 48% 45% 3% 0% 4%
endo- 3% 25% 42% 2% 28%