Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Protein alignment comparing the D. melanogaster and B. tryoni shibire. There is a high level of conservation between the two proteins (90% identity). Amino acid 268 is mutated in the shits1 mutant, which changes the glycine (G) residue to an aspartic acid (D) residue. Middle = Middle domain, PH = pleckstrin homology domain, GED = GTPase effector domain
