Figure 4.
Changes of VEGF and PEDF in the iBRB-Müller cell co-culture due to AGEs. (a) VEGF in the media of the in vitro iBRB-Müller cell co-culture model determined using ELISA after treatment with indicated AGEs for 24, 48, and 72 h. (b) PEDF in the media of the in vitro iBRB-Müller cell co-culture model determined using ELISA after treatment with indicated AGEs for 24, 48, and 72 h. *P < 0.05 compared with the vehicle control group; #P < 0.05 compared with the low-dose group at 24 h earlier; ‡P < 0.05 compared with the high-dose group, at the same time point.