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. 2020 Dec 17;10:22135. doi: 10.1038/s41598-020-79123-2

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© This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2020

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Molecular clock analysis reveals organization of the genomic island 1 via acquisition of distinct sub-elements. A timetree using the 7.1 KB consensus region in the 265 strains highlighted in black dashed box in Fig. 3 may offer clues towards the acquisition of sub-elements leading to the formation of GI1. Divergence times shown are relative times as no calibrations were provided. The estimated log likelihood value of the tree is − 14,227.79. The percentage of replicate trees in which the associated taxa clustered together in the bootstrap test are shown next to the branches. The phylogenetic tree is rooted using CD105KSE6. CD105KSE6 branches most distantly from RT106/ST28/ST42 clade based on alignment of the 7.1 kb region in GI1.