Table II.

Data summary of 34 diseased and 5 normal liver samples assessed for metallothionein and Ki-67 labelling, inflammation, fibrosis, and bile duct proliferation.

Case numbera	Inflammatory cellsb	Fibrosisc, 0–3	BDPd	MT-positive hepatocytese in 0.625 mm2	MT labelling intensityf, 0–3	Ki-67 positive hepatocytesg in 0.625 mm2
1	121.8	2	2.7	6.1	1.6	0
2	501.8	2.5	2.6	49	2	0.6
3	999.0	3	4	72.3	2.8	0
4	197.0	2	11.5	8.8	1.6	0
5	173.0	1.5	12.4	13.7	1.6	0
6	36.4	2.5	1.8	14.7	1.4	0
7	137.2	2.5	3	43.2	1.9	0.7
8	107.8	1.5	5.8	9.6	1.1	1.6
9	170.2	2	5.2	26.6	1.5	0
10	49.0	1.5	1.8	0.1	2	0.4
11	84.8	1	10.4	84.9	2.5	0
12	120.0	3	2.9	41.6	1.9	0
13	210.2	1.5	5.2	30.1	2.2	2.8
14	27.8	2.5	2.2	1	1.3	1.2
15	10.8	2	2.3	9.1	2	0.1
16	55.6	2	2.7	0.2	1.9	1.2
17	25.8	1.5	3	0	0.6	0
18	62.4	2	4.3	17.5	2	0.7
19	6.6	2	2	77.2	2.5	0
20	31.2	2	2.3	23.4	2	0
21	40.6	2	2.6	27.8	2.1	0
22	229.8	1.5	4.2	0.9	2.1	0
23	124.2	1.5	2.6	49.3	1.9	0
24	105.4	3	4.5	9	1.8	0
25	76.8	2	2.6	0	1.1	0
26	53.4	3	2.4	0.9	1.4	0
27	204.4	2.5	2.7	45.4	2.3	0
28	247.8	3	11.2	3.1	2.1	0
29	29.2	2.5	4.5	71.1	1.6	0
30	430.8	2.5	10.4	77.6	2	0.6
31	52.2	2.5	2.2	1.2	2	0
32	374.0	3	5	67.7	2.4	0
33	127.2	0.5	8.4	50.1	1.8	0
34	373.2	2	2.5	89.25	2.9	0.8
35	6.6	0	1.8	0.5	1.1	0.4
36	11.4	0	1.8	0.4	1.5	0
37	6.8	0	1.4	0.1	1.3	0
38	12.8	0	2	0.1	2.1	0
39	6.8	0	1.4	0	2	0

MT — metallothionein; BDP — bile duct proliferation.

^aCase number: 1–34, liver samples with chronic cholangiohepatitis; 35–39, normal liver samples.

^bMean number of inflammatory cells surrounding 5 random portal areas.

^cMean fibrosis score by 2 independent pathologists in 5 random HPF (40×).

^dMean number of bile ducts counted in 5 random portal areas by 2 independent pathologists.

^eMean number of hepatocytes with positive MT labelling in 10 random HPF (40×).

^FMean MT labelling intensity in 10 random HPF (40×).

^gMean number of hepatocytes with positive Ki-67 staining in 10 random HPF (40×).