Fig. 4. Structural alignment of RPC5-tWHD1 to Pol I and Pol III PICs.
a Structural alignment between S. cerevisiae RNA Pol II (PDB code: 5FYW) and RNA Pol III (PDB code: 6EU0). RPC5-tWHD1 (wheat) superimposition to yeast Tfg2 WHD (grey) leads to clashes with Bdp1 subunit stem motif (orange). b Structural alignment between S. cerevisiae RNA Pol I (PDB code: 5W66) and RNA Pol III (PDB code: 6EU0). RPC5-tWHD1 (wheat) superimposition to yeast A49 tWHD (grey) does not cause clashes with TFIIIB subunits Brf1 (green), TBP (pink) or Bdp1 (orange).