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. 2020 Dec 4;11:585984. doi: 10.3389/fphar.2020.585984

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Copyright © 2020 Ruan, Jin, Zeng, Ren, Xie, Ji, Wu, Wu and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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GSPE improved the survival rate and cardiac function of MI mice. (A) The survival rate of mice in the GEPE-treated group compared with the MI group (log-rank: p < 0.01). (n = 3 per group) (B) The heart/body weight ration of mice in different groups. (C) Representative M-mode echocardiographic images in short axis from each group, the relative indicators included are LVEF(%), FS(%), LVIDd(mm). Data analyzed are mean ± SD. *Significant difference compared with the control group, p < 0.05; significance compared with the MI group, p < 0.05. n = 3 per group.