TABLE 3.
Outcome | Summary RoB assessmenta | Indirectness | Imprecision | Inconsistency | Publication bias | Magnitude of effect | Confounder effectb | Overall |
---|---|---|---|---|---|---|---|---|
SGTP vs GT switch43,47,49,51 | Unclear | Direct | Precise | Consistent | No | Large | No | Moderate |
High-grade CIN; SGTP vs GT switch47,49–51 | Low | Direct | Precise | Consistent | No | Large | No | High |
Genotype risk discrimination; high-grade CIN; SGTP2,42,43,48,50–53 | Unclear | Direct | Precise | Consistent | No | Moderate | No | Moderate |
aSee RoB table (see Table 2).
bCofounder effect characterizes the degree to which all plausible confounders would tend to increase confidence in the estimated effect.