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. 2020 Oct 27;25(1):27–37. doi: 10.1097/LGT.0000000000000573

TABLE 4.

Cervical Intraepithelial Neoplasia 2 or Higher and CIN 3 or Higher 3, 5, 10-Year Risks Comparing SGTP With GS

Kitchener et al.51 (2014) and Gilham et al.50 (2019) Pooled HPV persistent SGTP GS HPV(+), then HPV(−) as referent HPV(−), then HPV(−) as referent
≥CIN 2 three-year risk51 12.9% 21.0% 6.2 0.59% 0.02%
≥CIN 3 three-year risk51 7.0% 13.5% 1.7% 0.17% 0%
≥CIN 3 five-year CIR; NILM50 7.0 (3.9–12.2) 11.3 (6.5–19.5) 0 0.13 (0.02–0.90) 0.05 (0.02–0.11)
≥CIN 3 ten-year CIR; NILM50 8.9 (5.4–14.5) 13.4 (8.0–22.0) 1.7 (0.2–11.3) 0.26 (0.06–1.03) 0.09 (0.05–0.17)
≥CIN 3 five-year CIR; low-grade cytologya50 14.5 (7.8–26.0) 23.7 (14.8–36.8) 5.1 (2.5–10.4) 1.6 (0.2–10.7) 0
≥CIN 3 ten-year CIR; low-grade cytology50 16.2 (9.0–28.0) 23.7 (14.8–36.8) 5.9 (3.0–11.4) 1.6 (0.2–10.7) 0

aLow-grade cytology = ASC-US and LSIL combined.