TABLE 3.
Consistency of HPV Results Detected by Xpert HPV Overall and in Each Channel (% Agreement and κ Coefficient) Between Self- and Clinician-Collected Samples in 705 Women From the Screening Population and 402 Women From the Referral Population
| HPV channel | Screening population (n = 705) | Referral population (n = 402) | ||||
|---|---|---|---|---|---|---|
| % agreement | κ | 95% CI | % agreement | κ | 95% CI | |
| Xpert HPV (all 14 genotypes)a | 86.8% | 0.720 | 0.669–0.771 | 89.3% | 0.622 | 0.476–0.726 |
| Selected 3 channelsb | 89.4% | 0.751 | 0.699–0.803 | 89.8% | 0.690 | 0.602–0.778 |
| HPV 16 | 97.3% | 0.815 | 0.734–0.895 | 97.1% | 0.923 | 0.880–0.966 |
| HPV 18, 45 | 94.5% | 0.744 | 0.668–0.82 | 91.8% | 0.755 | 0.677–0.833 |
| HPV 31, 33, 35, 52, 58 | 93.1% | 0.769 | 0.708–0.83 | 91.3% | 0.824 | 0.769–0.879 |
| HPV 51, 59 | 94.5% | 0.588 | 0.472–0.704 | 77.9% | 0.696 | 0.590–0.802 |
| HPV 39, 56, 66, 68 | 91.8% | 0.578 | 0.484–0.694 | 67.6% | 0.670 | 0.579–0.761 |
aPositive for HPV 16, and/or HPV 18, 45, and/or HPV 31, 33, 35, 52, 58, and/or HPV 51, 59, and/or HPV 39, 56, 66, 68.
bPositive for HPV 16, and/or HPV 18, 45, and/or HPV 31, 33, 35, 52, 58.