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A, Squamous cell carcinoma and dVIN—central tumor surrounded by a white heterogeneous plaque. B, Hypertrophic keratinizing dVIN with thick PK and wide elongated rete ridges, H&E ×100. C, Vesicular nuclei with marked enlargement and multiple nucleoli, H&E ×400. D, p16 is negative ×100. E, p53 is aberrant negative, ×100.
