TABLE 2.
Spectrum of Dyskeratosis in dVIN and VAM20
| Diagnosis | Surface features | Intercellular breakdown | Premature maturation | % of epithelium with cellular maturation |
|---|---|---|---|---|
| Nonkeratinizing dVIN | ||||
| Basaloid dVIN | Thin PK Erosion |
Uncommon | None | <10 |
| Intermediate dVIN | Thin PK Erosion |
Uncommon | None | 10–40 |
| Keratinizing dVIN | ||||
| Atrophic | Thin PK Normal |
Variable | None | 50–80 |
| Subtle | Normal Thin PK |
None | None | 60–90 |
| Traditional | Thin to thick PK/HK | Frequent | Frequent | 40–90 |
| Acantholytic | Thin to thick PK | Marked | Variable | 40–90 |
| Hypertrophic | Thin to thick PK/HK | Frequent | Frequent | 40–90 |
| VAM | Thick PK/HK | Variable | Frequent | >80 |