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HSV-1 Oncolytic Vectors discussed in this review.
| Oncolytic HSV-1 | Strain | Mutations | Transgene inserted |
Reference |
|---|---|---|---|---|
| T-VEC | JS-1 | γ34.5Δ, ICP47Δ | Human GM-CSF | (7) |
| BV49.5 | Patton | γ34.5Δ | BHV-1 UL49.5 | (42) |
| OV-CDH1 | Q1 | γ34.5Δ, ICP6- | Human CDH1 | (36) |
| rQNestin34.5 | F | γ34.5Δ, ICP6Δ | Nestin-Hsp68promoter-γ34.5 | (58) |
| RAMBO | F | γ34.5Δ, ICP6- | Human Vstat120 | (63) |
| rRp450 | KOS | ICP6Δ | Rat CYP2B1 gene | (66) |
